NISHIJIMA Takeshi
准教授
西島 壮 ニシジマ タケシ にしじま たけし
プロフィール
所属
東京都立大学人間健康科学研究科 ヘルスプロモーションサイエンス学域
大学教育センター
最終学歴・学位
筑波大学大学院人間総合科学研究科 修了 博士(体育科学)
専門・研究分野
運動/身体不活動と脳機能(スポーツ神経科学、運動生理学)
研究
研究テーマ
1.身体活動量と脳機能の相互連関
身体活動量は、脳によってどのように規定されているか?
身体活動量を増加・減少させる刺激は何か?
身体活動量の増加・減少により、脳機能はどのように変化・適応するのか?
2.脳機能に対する運動と栄養の相乗効果
機能性食品の摂取により、脳機能に対する運動の効果を高めることができるか?
研究キーワード
運動、身体活動、身体不活動、海馬、神経新生、神経栄養因子、情動(うつ・不安)
詳細情報
Funabashi D, Tsuchida R, Matsui T, Kita I, Nishijima T. Enlarged housing space and increased spatial complexity enhance hippocampal neurogenesis but do not increase physical activity in mice. Frontiers in Sports and Active Living, 5:1203260. doi: 10.3389/fspor.2023.1203260, 2023.
Tsuchida R, Yamaguchi T, Funabashi D, Koumi Y, Kita I, Nishijima T. Exercise type influences the effect of an acute bout of exercise on hippocampal neuronal activation in mice. Neuroscience Letters 783, 136707, 2022.
Funabashi D, Wakiyama T, Muto N, Kita I, Nishijima T. Social isolation is a direct determinant of decreased home‐cage activity in mice: A within‐subjects study using a body‐implantable actimeter. Experimental Physiology 107(2) 133-146, 2022.
Morikawa R, Kubota N, Amemiya S, Nishijima T, Kita I. Interaction between intensity and duration of acute exercise on neuronal activity associated with depression-related behavior in rats. The Journal of Physiological Sciences 71(1), doi: 10.1186/s12576-020-00788-5, 2021.
Amemiya S, Ishida M, Kubota N, Nishijima T, Kita I. Stress drives deliberative tendencies by influencing vicarious trial and error in decision making. Neurobiology of Learning and Memory, 107276-107276, 2020.
Kubota N, Amemiya S, Yanagita S, Nishijima T, Kita I. Central nucleus of the amygdala is involved in induction of yawning response in rats. Behavioual Brain Research 371: 111974. DOI: 10.1016/j.bbr.2019.11197, 2019.
Sato K, Nishijima T, Yokokawa T, Fujita S. Acute bout of exercise induced prolonged muscle glucose transporter-4 translocation and delayed counter-regulatory hormone response in type 1 diabetes. PLoS ONE, 12(6): e0178505, 2017.
Nishijima T*, Kamidozono Y, Ishiizumi A, Amemiya S, Kita I. Negative rebound in hippocampal neurogenesis following exercise cessation. Am J Physiol Regul Integr Comp Physiol, 313: R347-R357, 2017.
Trueba-Saiz A, Fernandez AM, Nishijima T, Santi A, Munive V, Mecha M, Torres-Aleman I. Circulating insulin like growth factor I regulates its receptor in the brain. Endocrinology, 158: 349-355, 2017.
Nishijima T*, Torres-Aleman I, Soya H. Exercise and cerebrovascular plasticity. Prog Brain Res, 225: 243-268, 2016.
Otsuka T, Nishii A, Amemiya S, Kubota N, Nishijima T, Kita I. Effects of acute treadmill running at different intensities on activities of serotonin and corticotropin-releasing factor neurons, and anxiety- and depressive-like behaviors in rats. Behav Brain Res, 298: 44-51, 2016.
Amemiya S, Kubota N, Umeyama N, Nishijima T, Kita I. Noradrenergic signaling in the medial prefrontal cortex and amygdala differentially regulates vicarious trial-and error in a spatial decision-making task. Behav Brain Res, 297: 104-111, 2016.
Nishijima T*, Kawakami M, Kita I. A bout of treadmill exercise increases matrix metalloproteinase-9 activity in the rat hippocampus. Neurosci Lett, 594: 144-149, 2015. (*corresponding author)
Nishijima T*, Kita I. Deleterious effects of physical inactivity on the hippocampus: New insight into the increasing prevalence of stress-related depression. J Phys Fitness Sports Med, 4: 253-258, 2015.
Inoue K, Hanaoka Y, Nishijima T, Okamoto M, Chang H, Saito T, Soya H. Long-term mild exercise training enhances hippocampus-dependent memory in rats. Int J Sports Med, in press.
Amemiya S, Noji T, Kubota N, Nishijima T, Kita I. Noradrenergic modulation of vicarious trial-and-error behavior during a spatial decision making task in rats. Neuroscience, 265: 291-301, 2014.
Kubota N, Amemiya S, Yanagita S, Nishijima T, Kita I. Emotional Stress evoked by classical fear conditioning induces yawning behavior in rats. Neurosci Lett, 566: 182-187, 2014.
Nishijima T, Kawakami M, Kita I. Long-term exercise is a potent trigger for ΔFosB induction in the hippocampus along the dorso-ventral axis. PLoS ONE, 8(11):e81245, 2013.
Nishijima T, Llorens-Martin M, Tejeda GS, Inoue K, Yamamura Y, Soya H, Trejo JL, Torres-Aleman I. Cessation of voluntary wheel running increases anxiety-like behavior and impairs adult hippocampal neurogenesis in mice. Behav Brain Res 245C:34-41, 2013
Nishijima T, Okamoto M, Matsui T, Kita I, Soya H. Hippocampal functional hyperemia mediated by NMDA receptor/NO signaling in rats during mild exercise. J Appl Physiol 112:197-203, 2012.
Kubota N, Amemiya S, Motoki C, Otsuka T, Nishijima T, Kita I. Corticotropin-releasing factor antagonist reduces activation of noradrenalin and serotonin neurons in the locus coeruleus and dorsal raphe in the arousal response accompanied by yawning behavior in rats. Neurosci Res 72:316-323, 2012.
Nishijima T*, Piriz J*, Duflot S*, Fernandez AM, Gaitan G, Gomez-Pinedo U, Verdugo JM, Leroy F, Soya H, Nunez A, Torres-Aleman I. Neuronal activity drives localized blood-brain-barrier transport of serum insulin-like growth factor-I into the CNS. Neuron 67:834-846, 2010. *contributed equally
Amemiya S, Yanagita S, Suzuki S, Kubota N, Motoki C, Otsuka T, Nishijima T, Kita I. Differential effects of background noise of various intensities on neuronal activation associated with arousal and stress response in a maze task. Physiol Behav 99:521-528, 2010
Timinkul A, Kato M, Omori T, Deocaris CC, Ito A, Kizuka T, Sakairi Y, Nishijima T, Asada T, Soya H. Enhancing effect of cerebral blood volume by mild exercise in healthy young men: a near-infrared spectroscopy study. Neurosci Res 61:242-248, 2008.
Soya H, Mukai A, Deocaris CC, Ohiwa N, Chang H, Nishijima T, Fujikawa T, Togashi K, Saito T. Threshold-like pattern of neuronal activation in the hypothalamus during treadmill running: establishment of a minimum running stress (MRS) rat model. Neurosci Res 58:341-348, 2007.
Soya H, Nakamura T, Deocaris CC, Kimpara A, Iimura M, Fujikawa T, Chang H, McEwen BS, Nishijima T. BDNF induction with mild exercise in the rat hippocampus. Biochem Biophys Res Commun 358:961-967, 2007.
Nishijima T, Soya H. Evidence of functional hyperemia in the rat hippocampus during mild treadmill running. Neurosci Res 54:186-191, 2006.
Nishijima T, Soya H. Hemodynamics under Hippocampal Functional Hyperemia in Anesthetized Rat: A Greater Contribution of Red Blood Cell Velocity Compared to Its Concentration. Jpn J Physiol 55:303-307, 2005.
Tsuchida R, Yamaguchi T, Funabashi D, Koumi Y, Kita I, Nishijima T. Exercise type influences the effect of an acute bout of exercise on hippocampal neuronal activation in mice. Neuroscience Letters 783, 136707, 2022.
Funabashi D, Wakiyama T, Muto N, Kita I, Nishijima T. Social isolation is a direct determinant of decreased home‐cage activity in mice: A within‐subjects study using a body‐implantable actimeter. Experimental Physiology 107(2) 133-146, 2022.
Morikawa R, Kubota N, Amemiya S, Nishijima T, Kita I. Interaction between intensity and duration of acute exercise on neuronal activity associated with depression-related behavior in rats. The Journal of Physiological Sciences 71(1), doi: 10.1186/s12576-020-00788-5, 2021.
Amemiya S, Ishida M, Kubota N, Nishijima T, Kita I. Stress drives deliberative tendencies by influencing vicarious trial and error in decision making. Neurobiology of Learning and Memory, 107276-107276, 2020.
Kubota N, Amemiya S, Yanagita S, Nishijima T, Kita I. Central nucleus of the amygdala is involved in induction of yawning response in rats. Behavioual Brain Research 371: 111974. DOI: 10.1016/j.bbr.2019.11197, 2019.
Sato K, Nishijima T, Yokokawa T, Fujita S. Acute bout of exercise induced prolonged muscle glucose transporter-4 translocation and delayed counter-regulatory hormone response in type 1 diabetes. PLoS ONE, 12(6): e0178505, 2017.
Nishijima T*, Kamidozono Y, Ishiizumi A, Amemiya S, Kita I. Negative rebound in hippocampal neurogenesis following exercise cessation. Am J Physiol Regul Integr Comp Physiol, 313: R347-R357, 2017.
Trueba-Saiz A, Fernandez AM, Nishijima T, Santi A, Munive V, Mecha M, Torres-Aleman I. Circulating insulin like growth factor I regulates its receptor in the brain. Endocrinology, 158: 349-355, 2017.
Nishijima T*, Torres-Aleman I, Soya H. Exercise and cerebrovascular plasticity. Prog Brain Res, 225: 243-268, 2016.
Otsuka T, Nishii A, Amemiya S, Kubota N, Nishijima T, Kita I. Effects of acute treadmill running at different intensities on activities of serotonin and corticotropin-releasing factor neurons, and anxiety- and depressive-like behaviors in rats. Behav Brain Res, 298: 44-51, 2016.
Amemiya S, Kubota N, Umeyama N, Nishijima T, Kita I. Noradrenergic signaling in the medial prefrontal cortex and amygdala differentially regulates vicarious trial-and error in a spatial decision-making task. Behav Brain Res, 297: 104-111, 2016.
Nishijima T*, Kawakami M, Kita I. A bout of treadmill exercise increases matrix metalloproteinase-9 activity in the rat hippocampus. Neurosci Lett, 594: 144-149, 2015. (*corresponding author)
Nishijima T*, Kita I. Deleterious effects of physical inactivity on the hippocampus: New insight into the increasing prevalence of stress-related depression. J Phys Fitness Sports Med, 4: 253-258, 2015.
Inoue K, Hanaoka Y, Nishijima T, Okamoto M, Chang H, Saito T, Soya H. Long-term mild exercise training enhances hippocampus-dependent memory in rats. Int J Sports Med, in press.
Amemiya S, Noji T, Kubota N, Nishijima T, Kita I. Noradrenergic modulation of vicarious trial-and-error behavior during a spatial decision making task in rats. Neuroscience, 265: 291-301, 2014.
Kubota N, Amemiya S, Yanagita S, Nishijima T, Kita I. Emotional Stress evoked by classical fear conditioning induces yawning behavior in rats. Neurosci Lett, 566: 182-187, 2014.
Nishijima T, Kawakami M, Kita I. Long-term exercise is a potent trigger for ΔFosB induction in the hippocampus along the dorso-ventral axis. PLoS ONE, 8(11):e81245, 2013.
Nishijima T, Llorens-Martin M, Tejeda GS, Inoue K, Yamamura Y, Soya H, Trejo JL, Torres-Aleman I. Cessation of voluntary wheel running increases anxiety-like behavior and impairs adult hippocampal neurogenesis in mice. Behav Brain Res 245C:34-41, 2013
Nishijima T, Okamoto M, Matsui T, Kita I, Soya H. Hippocampal functional hyperemia mediated by NMDA receptor/NO signaling in rats during mild exercise. J Appl Physiol 112:197-203, 2012.
Kubota N, Amemiya S, Motoki C, Otsuka T, Nishijima T, Kita I. Corticotropin-releasing factor antagonist reduces activation of noradrenalin and serotonin neurons in the locus coeruleus and dorsal raphe in the arousal response accompanied by yawning behavior in rats. Neurosci Res 72:316-323, 2012.
Nishijima T*, Piriz J*, Duflot S*, Fernandez AM, Gaitan G, Gomez-Pinedo U, Verdugo JM, Leroy F, Soya H, Nunez A, Torres-Aleman I. Neuronal activity drives localized blood-brain-barrier transport of serum insulin-like growth factor-I into the CNS. Neuron 67:834-846, 2010. *contributed equally
Amemiya S, Yanagita S, Suzuki S, Kubota N, Motoki C, Otsuka T, Nishijima T, Kita I. Differential effects of background noise of various intensities on neuronal activation associated with arousal and stress response in a maze task. Physiol Behav 99:521-528, 2010
Timinkul A, Kato M, Omori T, Deocaris CC, Ito A, Kizuka T, Sakairi Y, Nishijima T, Asada T, Soya H. Enhancing effect of cerebral blood volume by mild exercise in healthy young men: a near-infrared spectroscopy study. Neurosci Res 61:242-248, 2008.
Soya H, Mukai A, Deocaris CC, Ohiwa N, Chang H, Nishijima T, Fujikawa T, Togashi K, Saito T. Threshold-like pattern of neuronal activation in the hypothalamus during treadmill running: establishment of a minimum running stress (MRS) rat model. Neurosci Res 58:341-348, 2007.
Soya H, Nakamura T, Deocaris CC, Kimpara A, Iimura M, Fujikawa T, Chang H, McEwen BS, Nishijima T. BDNF induction with mild exercise in the rat hippocampus. Biochem Biophys Res Commun 358:961-967, 2007.
Nishijima T, Soya H. Evidence of functional hyperemia in the rat hippocampus during mild treadmill running. Neurosci Res 54:186-191, 2006.
Nishijima T, Soya H. Hemodynamics under Hippocampal Functional Hyperemia in Anesthetized Rat: A Greater Contribution of Red Blood Cell Velocity Compared to Its Concentration. Jpn J Physiol 55:303-307, 2005.
the Tokyo U-club、都市に関する研究奨励賞、最優秀賞(2014年)
日本体力医学会大会 若手奨励賞(2004年)
日本体力医学会大会 若手奨励賞(2004年)
Society for Neuroscience
日本体力医学会(評議員、総務委員会委員)
日本神経科学学会
日本体育・スポーツ・健康学会(政策検討・諮問委員会委員、IJSHS編集委員会委員)
日本生理学会(評議員)
日本運動生理学会
日本バドミントン学会(編集出版委員会委員長)
日本体力医学会(評議員、総務委員会委員)
日本神経科学学会
日本体育・スポーツ・健康学会(政策検討・諮問委員会委員、IJSHS編集委員会委員)
日本生理学会(評議員)
日本運動生理学会
日本バドミントン学会(編集出版委員会委員長)
- 人間健康科学概論
- 応用神経科学
- ヘルスプロモーションサイエンス特別研究a
- 行動科学特別講義
- スポーツ神経科学特論
- ヘルスプロモーションサイエンス特別研究a
- ヘルスプロモーションサイエンス特講Ⅱ
- ヘルスプロモーションサイエンス特別研究a
- ヘルスプロモーションサイエンス特別研究b
- ヘルスプロモーションサイエンス特別研究b
- ヘルスプロモーションサイエンス特別研究a
- ヘルスプロモーションサイエンス特別研究b
- ヘルスプロモーションサイエンス特別研究b
- 研究室インターンシップ(生体理工学)
- 研究室インターンシップ(生体理工学)
- スポーツ・健康と脳科学
- 身体運動学
- スポーツ実習(冬季集中)
- スポーツ実習(M2)
- 組織再編前旧課程の同時開講科目等が含まれており、掲載されている全ての科目を開講するわけではありません。
関連ニュース
すべて見る連絡先
研究室
13号館218号室
オフィスアワー
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内線番号
内線5044
メールアドレス
t-nishijima●tmu.ac.jp
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