Matsuura, Y., Noguchi, A., Yokota, N., and Kawahara, H. (2020) Nuclear accumulation of ZFP36L1 is cell cycle-dependent and determined by a C-terminal serine-rich cluster. J. Biochem. 168, 477-489.

Mimami, S., Yokota, N., and Kawahara, H. (2020) BAG6 contributes glucose uptake by supporting the cell surface translocation of the glucose transporter GLUT4. Biol. Open. 9, bio047324.

Takahashi, T., Minami, S., Tajima, K., Tsuchiya, Y., Sakai, N., Suga, K., Hisanaga, S., Obayashi, N., Fukuda, M., and Kawahara, H. (2019) Cytoplasmic control of Rab-family small GTPases through BAG6. EMBO Rep. 20: e46794

Kamikubo, K., Kato, H., Kioka, H., Yamazaki, S., Tsukamoto, O., Nishida, Y., Asano, Y., Imamura, H., Kawahara, H., Shintani, Y., and Takashima, S. (2019) A molecular triage process mediated by RING finger protein 126 and BCL2-associated athanogene 6 regulates degradation of G0/G1 switch gene 2. J. Biol. Chem. 294, 14562-14573.

Demizu, S., Asaka, M., Kawahara, H. and Sasaki, E. (2019) TAS-203, an oral phosphodiesterase 4 inhibitor, suppresses goblet cell hyperplasia and MUC5AC production in rodent models. Eur. J. Pharmacol. 849, 22-29.

Hayashishita, M., Kawahara, H., and Yokota N. (2019) BAG6 deficiency induces mis-distribution of mitochondrial clusters under depolarization. FEBS Open Bio. 9, 1281-1291.

Kondo, M., Noguchi, A., Matsuura, Y., Shimada, M., Yokota, N., and Kawahara, H. (2018) Novel phosphorelay-dependent control of ZFP36L1 protein during the cell cycle. Biochem. Biophys. Res. Comm. 501; 387-393.

Xuan, X., Matsumoto, S., Endo, S., Fukushima, A., Kawahara, H., Saeki, Y., and Komada, M. (2018) Deubiquitinases USP5 and USP13 are recruited to and regulate heat-induced stress granules by deubiquitinating activities. J. Cell Sci. 131, 1-11.

Noguchi, A., Adachi, S., Yokota, N., Hatta, T., Natsume, T., and Kawahara, H. (2018) ZFP36L2 is a cell cycle-regulated CCCH-protein necessary for DNA lesion-induced S-phase arrest. Biol. Open 7, bio031575

Yamamoto, K., Hayashishita, M., Minami, S., Suzuki, K., Hagiwara, T., Noguchi, A., and Kawahara, H. (2017) Elimination of a signal-sequence uncleaved form of defective HLA protein through BAG6. Sci. Rep. 7, DOI:10.1038/s41598-017-14975-9

Suzuki, R. and Kawahara, H. (2016) UBQLN4 recognizes mislocalized transmembrane domain proteins and targets these to proteasomal degradation. EMBO Rep. 17, 842？857.

Tanaka, H., Takahashi, T., Xie, Y., Minami, R., Yanagi, Y., Hayashishita, M., Suzuki, R., Yokota, N., Shimada, M., Mizushima, T., Kuwabara, N., Kato, R., and Kawahara, H. (2016) A conserved island of BAG6/Scythe is related to ubiquitin domains and participates in short hydrophobicity recognition. FEBS J. 283, 662？677. DOI: 10.1111/febs.13618

Takasugi, T., Minegishi, S., Asada, A., Saito, T., Kawahara, H. and Hisanaga, S.-I. (2016) Two degradation pathways of the p35 Cdk5 activation subunit, dependent and independent of ubiquitination. J. Biol. Chem. 291, 4649-4657. doi: 10.1074/jbc.M115.692871

Yamaki, Y., Kagawa, H., Hatta, T., Natsume, T., and Kawahara, H. (2016) The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes. Mol. Cell. Biochem. 414: 1-12. DOI: 10.1007/s11010-015-2643-4

Kuwabara, N., Minami, R., Yokota, N., Matsumoto, H., Senda, T., Kawahara, H., and Kato, R. (2015) Structure of a BAG6？Ubl4a complex reveals a novel binding interface that functions in tail-anchored protein biogenesis. J. Biol. Chem. 290, 9387-9398.

Kawahara, H., Minami, R. and Yokota, N. (2013) JB Review: BAG6 / BAT3: Emerging roles in quality control for nascent polypeptides. J. Biochem. 153, 147-160.

Kagawa, H.,, Shino, Y., Kobayashi, D., Demizu, S., Shimada. M., Ariga, H. and Kawahara, H. (2011) A novel signaling pathway mediated by the nuclear targeting of C-terminal fragments of mammalian Patched 1. PLoS ONE 6: e18638. doi:10.1371/journal.pone.0018638

Sato, K., Minegishi, S., Takano, J., Plattner, F., Saito, T., Asada, A., Kawahara, H., Iwata, N., Saido, T.C., and Hisanaga, S. (2011) Calpastatin, an endogenous calpain-inhibitor protein, regulates the cleavage of the Cdk5 activator p35 to p25. J. Neurochem. 117:504-515.

Minami, R., Hayakawa, A., Kagawa, H., Yanagi, Y., Yokosawa, H. and Kawahara, H. (2010) BAG-6 is essential for selective elimination of defective proteasomal substrates. J. Cell Biol. 190: 637-650.

Ojima, K., Y Kawabata, Y., Nakao, H., Nakao, K., Doi, N., Kitamura, F., Ono, Y., Hata, S., Suzuki, H., Kawahara, H., Labeit, S., Toyama-Sorimachi, N., Suzuki, K., Maeda, T., Abe, K., Aiba, A., and Sorimachi, H. (2010) Role of dynamic distribution of muscle-specific calpain in physical-stress adaptation and muscular dystrophy in mice. J. Clinc. Invest. 120: 2672－2683.

Endo, R., Saito, T., Asada, A., Kawahara, H. and Hisanaga, S.-I. (2009) Commitment of 1-methyl-4-phenylpyrinidinium ion-induced neuronal cell death by proteasome-mediated degradation of p35 Cyclin-dependent kinase 5 activator. J. Biol. Chem. 284, 26029-26039.

Minami, R., Shimada, M., Yokosawa, H. and Kawahara, H. (2007) Scythe regulates apoptosis through modulating ubiquitin-mediated proteolysis of XEF1AO. Biochem. J. (London) 405: 495-501.

Hamazaki, J., Sasaki, K., Kawahara, H., Hisanaga, S., Tanaka, K., and Murata, S. (2007) Rpn10-mediated degradation of ubiquitinated proteins is essential for mouse development. Mol. Cell. Biol. 27: 5529-6638.

Tayama, Y., Kawahara, H., Minami, R., Shimada, M., and Yokosawa, H. (2007) Association of Rpn10 with high molecular weight complex is enhanced during retinoic acid-induced differentiation of neuroblastoma cells. Mol. Cell. Biochem.

Shimada, M., Kanematsu, K., Tanaka, K., Yokosawa, H. and Kawahara, H. (2006) Proteasomal ubiquitin receptor RPN-10 controls sex determination in Caenorhabditis elegans. Mol. Biol. Cell 17: 5356-5371.

Shimada, M., Yokosawa, H., and Kawahara, H. (2006) OMA-1 is a P granules-associated protein that is required for germline specification in C. elegans. Genes Cells 11, 383-396.

Hata, S., Koyama, S., Kawahara, H., Doi, N., Maeda, T., Toyama-Sorimachi, N., Abe, K., Suzuki, K., and Sorimachi, H. (2006) Stomach-specific calpain localizes in mucus cells and proteolyses the β-subunit of coatomer complex, β-COP. J. Biol. Chem. 281, 11214-11224.

Kikukawa, Y., Minami, R., Shimada, M., Kobayashi, M., Tanaka, K., Yokosawa, H., and Kawahara, H. (2005) Unique proteasome subunit Xrpn10c is a specific receptor for the antiapoptotic ubiquitin-like protein Scythe. FEBS J. 272, 6373－6386.

Saeki, Y., Isono, E., Shimada, M., Kawahara, H., Yokosawa, H., and Toh-e, A. (2005) Knocking out ubiquitin proteasome system function in vivo and in vitro with genetically-encodable tandem ubiquitin. Methods Enzymol. 399, 64-74.

Kinouchi, T., Ishiura, S., Mabuchi, Y., Urakami-Manaka, Y., Nishio, H., Nishiuchi, Y., Tsunemi, M., Takada, K., Watanabe, M., Ikeda, M., Matsui, H., Tomioka, S., Kawahara, H., Hamamoto, T., Suzuki, K., Kagawa, Y. (2004) Mammalian D-aspartyl endopeptidase: a scavenger for noxious racemized proteins in aging. Biochem. Biophys. Res. Comm. 314, 730-736.

Tsukamoto, S., Yamashita, K., Tane, K., Kizu, R., Ohta, T., Matsunaga, S., Fusetani, N., Kawahara, H., and Yokosawa, H. (2004) Girolline, an antitumor compound isolated from a sponge, induces G2/M cell cycle arrest and accumulation of polyubiquitinated p53. Biol. Pharm. Bull. 27, 699-701.

Saeki, Y., Isono, E., Oguchi, T., Shimada, M., Sone, T., Kawahara, H., Yokosawa, H., and Toh-e, A. (2004) Intracellularly inducible, ubiquitin hydrolase-insensitive tandem ubiquitins inhibit the 26S proteasome activity and cell division. Genes Genet. Syst. 79, 77-86.

Sakata, E., Yamaguchi, Y., Kurimoto, E., Kikuchi, J., Yokoyama, S., Yamada, S., Kawahara, H., Yokosawa, H., Hattori, N., Mizuno, Y., Tanaka, K. and Kato. K. (2003) Parkin binds the Rpn10 subunit of the 26S proteasome with the ubiquitin-like domain. EMBO Rep. 4, 301-306.

Sato, N., Kawahara, H., Toh-e, A. and Maeda, T. (2003) Phosphorelay-regulated degradation of the yeast Ssk1p response regulator by the ubiquitin-proteasome system. Mol. Cell. Biol. 23, 6662-6671.

Kawai, N., Shimada, M., Kawahara, H., Satoh, N. and Yokosawa, H. (2003) Regulation of ascidian Rel by its alternative splice variant. Eur. J. Biochem. 270, 4459-4468.

Shimada, M., Kawahara, H., and Doi, H. (2002) Novel family of CCCH type Zinc-finger proteins; MOE-1, -2 , and -3, participate in C. elegans oocyte maturation. Genes Cells 7, 933-947.

Kikukawa, Y., Shimada, M., Suzuki, N., Tanaka, K., Yokosawa, H., and Kawahara, H. (2002) The 26S proteasome rpn10 gene encoding splicing isoforms: evolutional conservation of the genomic organization in vertebrates. Biol. Chem. 383, 1257-1261.

Takahashi, N., Sasagawa, N., Usuki, F., Kino, Y., Kawahara, H., Sorimachi, H., Maeda, T., Suzuki, K., and Ishiura, S. (2001) Coexpression of the CUG-binding protein reduces DM protein kinase expression in COS cells. J. Biochem. 130, 581-587.

Umeda, T., Kouchi, Z., Kawahara, H., Tomioka, S., Sasagawa, N.,Maeda, T., Sorimachi, H., Ishiura, S., and Suzuki, K. (2001) Limited proteolysis of filamin is catalyzed by caspase-3 in U937 and Jurkat cells. J. Biochem. 130, 535-542.

Hata, S., Nishi, K., Kawamoto, T., Lee, H.J., Kawahara, H., Maeda, T., Sorimachi, H., Suzuki, K. (2001) Both the conserved and the unique gene structure of stomach-specific calpains reveal processes of calpain gene evolution. J. Mol. Evol. 53, 191-203.

Kawahara, H., Philipova, R., Yokosawa, H., Patel, R., Tanaka, K. and Whitaker, M. (2000) Inhibiting proteasome activity causes over-replication of DNA and blocks entry into mitosis in sea urchin embryos. J. Cell Sci. 113, 2659-2670.

Kawahara, H., Kasahara, M., Nishiyama, A., Ohsumi, K., Goto, T., Kishimoto, T., Saeki, Y., Yokosawa, H., Shimbara, N., Mutrata, S., Chiba, T., Suzuki, K. and Tanaka, K. (2000) Developmentally regulated alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes. EMBO J. 19, 4144-4153.

Murata, S., Kawahara, H., Tohma, S., Kasahara, K., Tanaka, K. and Chiba, T. (1999) Growth retardation of mice lacking the proteasome activator PA28 γ. J. Biol. Chem. 274, 38211-38215.

川原 裕之（2021）プレエンプティブ品質管理を介した不良タンパク質のサーベイランスとその意義
月刊「細胞」 第53巻 pp.179 - 181.

川原 裕之、南 雪也、宮内 真帆、高橋 俊樹 (2020)「プレエンプティブ品質管理を介した膜タンパク質の選択的分解機構」
生化学 第92巻第2号, pp.1-6.

川原裕之(2018)「膜／分泌タンパク質の生合成プロセスを監視するプレエンプティブ品質管理」医学のあゆみ

川原裕之(2015)「ユビキチンによるタンパク質品質管理と疾患」The World of UBIQUITIN　Vol. 3

川原裕之, 南亮介 (2011)「BAG6を介したタンパク質品質管理の新機構」実験医学、第29巻、

嶋田益弥、川原裕之（2010）「卵成熟制御におけるCCCH型zinc-finger蛋白質の機能」「細胞周期フロンティア」共立出版

川原裕之, 横沢英良 (2008)「ユビキチン依存的蛋白質分解系の新しい仕組み：ポリユビキチン鎖の認識とプロテアソームへの運搬」
癌と化学療法, 　癌と化学療法社　1月号　　35巻 p11-15
川原裕之, 嶋田益弥, 南亮介, 横沢英良 (2006)「ユビキチンレセプターの構造と機能」蛋白質核酸酵素, 増刊号pp.1245-1250,共立出版

佐伯泰, 川原裕之, 横沢英良 (2003)「ユビキチンと相互作用するドメイン構造」実験医学、21,　340-345, 羊土社

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