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西島 壮

氏 名西島 壮ニシジマ タケシにしじま たけし
職 位准教授
所 属首都大学東京人間健康科学研究科 ヘルスプロモーションサイエンス学域
大学教育センター
 
専門・研究分野運動/身体不活動と脳機能(スポーツ神経科学、運動生理学)
最終学歴・学位筑波大学大学院人間総合科学研究科 修了 博士(体育科学)
研究テーマ身体不活動は海馬神経機能を低下させ、うつ病発症リスクを高めるか?
運動による抗うつ・抗不安効果の分子基盤の解明:海馬神経機能に着目して
環境ストレスが運動学習に及ぼす影響:ストレスの強さに着目して
研究キーワード運動、不活動、海馬、神経新生、神経栄養因子、情動(うつ・不安)
研究業績・著書・
論文、その他
それに準じる業績
1. Nishijima T*, Torres-Aleman I, Soya H. Exercise and cerebrovascular plasticity. Prog Brain Res, 225: 243-268, 2016.
2. Otsuka T, Nishii A, Amemiya S, Kubota N, Nishijima T, Kita I. Effects of acute treadmill running at different intensities on activities of serotonin and corticotropin-releasing factor neurons, and anxiety- and depressive-like behaviors in rats. Behav Brain Res, 298: 44-51, 2016.
3. Amemiya S, Kubota N, Umeyama N, Nishijima T, Kita I. Noradrenergic signaling in the medial prefrontal cortex and amygdala differentially regulates vicarious trial-and error in a spatial decision-making task. Behav Brain Res, 297: 104-111, 2016.
4. Nishijima T*, Kawakami M, Kita I. A bout of treadmill exercise increases matrix metalloproteinase-9 activity in the rat hippocampus. Neurosci Lett, 594: 144-149, 2015. (*corresponding author)
5. Nishijima T*, Kita I. Deleterious effects of physical inactivity on the hippocampus: New insight into the increasing prevalence of stress-related depression. J Phys Fitness Sports Med, 4: 253-258, 2015.
6. Inoue K, Hanaoka Y, Nishijima T, Okamoto M, Chang H, Saito T, Soya H. Long-term mild exercise training enhances hippocampus-dependent memory in rats. Int J Sports Med, 36(4): 280-285, 2014.
7. Kubota N, Amemiya S, Yanagita S, Nishijima T, Kita I. Emotional stress evoked by classical fear conditioning induces yawning behavior in rats. Neurosci Lett, 566: 182-187, 2014.
8. Amemiya S, Noji T, Kubota N, Nishijima T, Kita I. Noradrenergic modulation of vicarious trial-and-error behavior during a spatial decision-making task in rats. Neuroscience, 265: 291-301, 2014.
9. Nishijima T*, Kawakami M, Kita I. Long-term exercise is a potent trigger for delta FosB induction in the hippocampus along the dorso-ventral axis. PLoS One 8 (11): eB1245. doi:10.1371/journal.pone.0081245, 2013. (*corresponding author)
10. Nishijima T*, Llorens-Martin M, Tejeda GS, Inoue K, Yamamura Y, Soya H, Trejo JL, Torres-Aleman I. Cessation of voluntary wheel running increases anxiety-like behavior and impairs adult hippocampal neurogenesis in mice. Behav Brain Res, 245(15): 32-41, 2013. (*corresponding author)
11. Kubota N, Amemiya S, Motoki C, OtsukaT, Nishijima T, Kita I. Corticotropin-releasing factor antagonist reduces activation of noradrenalin and serotonin neurons in the locus coeruleus and dorsal raphe in the arousal response accompanied by yawning behavior in rats, Neurosci Res, 72(4): 216-323, 2012.
12. Nishijima T, Okamoto M, Matsui T, Kita I, Soya. Hippocampal functional hyperemia mediated by NMDA receptor/NO signaling in rats during mild exercise. J Appl Physiol, 112(1): 197-203, 2012.
13. Soya H, Okamoto M, Matsui T, Lee M, Inoue K, Soya S, Nishikawa S, Fujikawa T, Chang H, Nishijima T. Brain activation through exercise: study on exercise conditions which leads to neuronal activation and hippocampal neurogenesis. J Exerc Nutr Biochem 15, 1-10, 2011.
14. Nishijima T*, Piriz J*, Duflot S*, Fernandez AM, Gaitan G, Gomez-Pinedo U, Garcia Verdugo JM, Leroy F, Soya H, Nunes A, and Torres-Aleman I. Neuronal Activity Drives Localized Blood-Brain-Barrier Transport of Serum Insulin-like Growth Factor-I into the CNS. Neuron. 67(5): 834-846, 2010. (* contributed equally)
15. Amemiya S, Yanagita S, Suzuki S, Kubota N, Motoki C, Otsuka T, Nishijima T, Kita I. Differential effects of background noise of various intensities on neuronal activation associated with arousal and stress resonse in a maze task. Physiol Behav, 99(4): 521-528, 2010.
16. Soya H, Deocaris CC, Yamaguchi K, Ohiwa N, Saito T, Nishijima T, Kato M, Tateoka M, Matsui T, Okamoto M, Fujikawa T. Extract from Acanthopanax senticosus harms (Siberian ginseng) activates NTS and SON/PVN in the rat brain. Biosci Biotechnol Biochem. 72(9): 2476-2480, 2008.
17. Timinkul A, Kato M, Omori T, Deocaris CC, Ito A, Kizuka T, Sakairi Y, Nishijima T, Asada T, Soya H, Enhancing effect of cerebral blood volume by mild exercsie in healthy young men: A near-infrared spectroscopy study. Neurosci Res. 61(3): 242-248, 2008.
18. Soya H, Mukai A, Deocaris CC, Ohiwa N, Chang H, Nishijima T, Fujikawa T, Togashi K, Saito T. Threshold-like pattern of neuronal activation in the hypothalamus during treadmill running: Establishment of a minimum running stress (MRS) rat mode. Neurosci Res. 58(4): 341-348, 2007.
19. Soya H, Nakamura T, Deocaris CC, Kimpara A, Iimura M, Fujikawa T, Chang H, McEwen BS, Nishijima T. BDNF induction with mild exercise in the rat hippocampus. Biochem Biophys Res Commun. 358(4): 961-967, 2007.
20. Nishijima T, Tashiro H, Kato M, Saito T, Omori T, Chang H, Ohiwa N, Sakairi Y, Soya H, Alleviation of exercise-induced dehydration under hot condition by glycerol hyperhydration. Int J Sport Health Sci. 5: 32-41, 2007.
21. Nishijima T, Soya H, Evidence of functional hyperemia in the rat hippocampus during mild treadmill running. Neurosci Res(3), 54: 186-191, 2006.
22. Nishijima T, Soya H, Hemodynamics under hippocampal functional hyperemia in anesthesized rats: a greater contribution of red blood cells velocity compared to its concentration. Jpn J Physiol, 55(5): 303-307, 2005.
受 賞the Tokyo U-club、都市に関する研究奨励賞、最優秀賞(2014年)
日本体力医学会大会 若手奨励賞(2004年)
主な学会活動Society for Neuroscience
日本体力医学会(評議員)
日本神経科学学会
日本体育学会
日本生理学会
日本運動生理学会
社会等との関わり
個人のURL
担当科目
  • 運動行動学
  • 身体運動演習
  • 身体運動演習
  • スポーツ実習
  • 身体運動学
  • スポーツ実習B
  • 生理学実験(身体運動科学)
  • ヘルスプロモーションサイエンス特講Ⅱ
  • 運動行動学
  • 身体運動演習
  • 身体運動演習
  • スポーツ実習
  • 身体運動学
  • スポーツ実習B
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取組状況平成27年度
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