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三島 正規

氏 名三島 正規ミシマ マサキみしま まさき  
職 位准教授
所 属首都大学東京都市教養学部 理工学系 化学コース
理工学研究科 分子物質化学専攻
 
専門・研究分野有機構造生物化学
核磁気共鳴分光法
生物物理学
分子生物学
最終学歴・学位奈良先端科学技術大学院大学 博士後期過程修了 博士
研究テーマ(1)生体高分子の立体構造決定に基づく分子レベルでの生命現象の解明
(2)構造解析のためのNMR分光法の開発
研究キーワード核磁気共鳴分光法、NMR、有機構造生物化学、分子生物学、構造生物学
研究業績・著書・
論文、その他
それに準じる業績
(1) “Structural basis for tubulin recognition cytoplasmic linker protein 170 and its autoinhibition”
Masaki Mishima, Ryoko Maesaki, Miyuki Kasa, Takashi Watanabe, Masaki Fukata, Kozo Kaibuchi and Toshio Hakoshima
Proc. Natl. Acad. Sci. U S A. 2007 104(25):10346-51

(2)“Solution structure of the cytoplasmic region of Na+/H+ exchanger 1 complexed with essential cofactor calcineurin B homolog protein 1.”
Masaki Mishima, Shigeo Wakabayashi and Chojiro Kojima,
Journal of Biological Chemistry 2007 282(4):2741-51

(3) “1H, 13C and 15N resonance assignments of the VAP-A: OSBP complex. ”
Kyoko Furuita, Masaki Mishima, and Chojiro Kojima
Journal of Biomolecular NMR 2006 Suppl 5:69

(4) “Solution structure of the peptidoglycan binding domain of B. subtilis cell wall lytic enzyme CwlC: Characterization of the sporulation-related repeats by NMR.”
Masaki Mishima, Toshio Shida, Kazuto Yabuki, Ken-ichi Kato, Junichi Sekiguchi and Chojiro Kojima
Biochemistry 2005 44(30):10153-10163

(5) “Small-molecule ligand induces nucleotide flipping in (CAG)n trinucleotide repeats.”
Kazuhiko Nakatani, Shinya Hagihara, Yuki Goto, Akio Kobori, Masaki Hagihara, Gosuke Hayashi, Motoki Kyo, Makoto Nomura, Masaki Mishima, and Chojiro Kojima
Nature Chemical Biology 2005 1:39-43

(6) “Linker Region of a Halobacterial Transducer Protein Interacts Directly with Its Sensor Retinal Protein.”
Yuki Sudo, Hideyasu Okuda, Masaki Yamabi, Yuta Fukuzaki, Masaki Mishima, Naoki Kamo, and Chojiro Kojima
Biochemistry 2005 44(16):6144-6152

(7) “Amino Acid Residues Involved in Substrate Recognition of the Escherichia coli Orf135 Protein.”
Emiko Iida, Kazuya Satou, Masaki Mishima, Chojiro Kojima, Hideyoshi Harashima, and Hiroyuki Kamiya
Biochemistry 2005 44(15):5683-5689

(8) “Backbone and side-chain assignments of the rice phytochrome B PAS1 domain and backbone assignments of the PAS1-PAS2 domain.”
Toshitatsu Kobayashi, Masaki Mishima, Kayo Akagi, Nobuya Sakai, Etsuko Katoh, Makoto Takano, Toshimasa Yamazaki and Chojiro Kojima
Journal of Biomolecular NMR 2005 31(3):269-270

(9) “High-throughput construction method for expression vector of peptides for NMR study suited for isotopic labeling.”
Takeshi Tenno, Natsuko Goda, Yukihiro Tateishi, Hidehito Tochio, Masaki Mishima, Hidenori Hayashi, Masahiro Shirakawa, and Hidekazu Hiroaki
Protein Engineering Design and Selection 2004 17(4):305-314.

(10) “Autoantigenicity of DFS70 is restricted to the conformational epitope of C-terminal alpha-helical domain.”
Yasushi Ogawa, Kazumitsu Sugiura, Akihiro Watanabe, Mitoshi Kunimatsu, Masaki Mishima, Yasushi Tomita, and Yoshinao Muro
Journal of Autoimmunity 2004 23(3):221-231

(11) “Paramagnetic NMR study of Cu2+-IDA complex localization on a protein surface and its application to elucidate long distance information.”
Makoto Nomura, Toshitatsu Kobayashi, Toshiyuki Kohno, Kenichiro Fujiwara, Takeshi Tenno, Masahiro Shirakawa, Itsuko Ishizaki, Kazuo Yamamoto, Toshifumi Matsuyama, Masaki Mishima, and Chojiro Kojima
FEBS Letter 2004 566(1-3):157-161

(12) “Structure of the human oxidized purine nucleoside triphosphatase, human MTH1.”
Masaki Mishima, Yasunari Sakai, Noriyuki Itoh, Hiroyuki Kamiya, Masato Furuichi, Masayuki Takahashi, Shigenori Iwai, Yusaku Nakabeppu, and Masahiro Shirakawa
Journal of Biological Chemistry, 2004 279(32): 33806-33815

(13) “MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain.”
Yohei Tominaga, Yasuhiro Ushijima, Daisuke Tsuchimoto, Masaki Mishima, Masahiro Shirakawa, Seiki Hirano, Kunihiko Sakumi, and Yusaku Nakabeppu
Nucleic Acids Research 2004 32(10):3198-3211

(14) “Structure of the male determinant factor for Brassica self-incompatibility.”
Masaki Mishima, Seiji Takayama, Kei-ichi Sasaki, Jun-Goo Jee, Chojiro Kojima, Akira Isogai, and Masahiro Shirakawa
Journal of Biological Chemistry 2003 278(38): 36389-36395

(15) “The structure and binding mode of interleukin-18.”
Zenichiro Kato, Jun-goo Jee, Hiroaki Shikano, Masaki Mishima, Izuru Ohki, Hidenori Ohnishi, Ailian Li, Kazuyuki Hashimoto, Eiji Matsukuma, Kentaro Omoya, Yutaka Yamamoto, Teruyo Yoneda, Takane Hara, Naomi Kondo, and Masahiro Shirakawa
Nature Structural Biology 2003 10(11):966-971

(16) “Role of tryptophan residues in the recognition of mutagenic oxidized nucleotides by human antimutator MTH1 protein.”
Masayuki Takahashi, Fabrice Maraboeuf, Yasunari Sakai, Hiroyuki Yakushiji, Masaki Mishima, Masahiro Shirakawa, Shigenori Iwai, Hiroshi Hayakawa, Mutsuo Sekiguchi, and Yusaku Nakabeppu
Journal of Molecular Biology 2002 319(1):129-139

(17) “A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1.”
Yasunari Sakai, Masato Furuichi, Masayuki Takahashi, Masaki Mishima, Shigenori Iwai, Masahiro Shirakawa, and Yusaku Nakabeppu
Journal of Biological Chemistry 2002 277(10):8579-8587

(18) “Intermolecular 31P-15N and 31P-1H scalar couplings across hydrogen bonds formed between a protein and a nucleotide.”
Masaki Mishima, Minoru Hatanaka, Shigeyuki Yokoyama, Takahisa Ikegami, Markus W?lchli, Yutaka Ito, and Masahiro Shirakawa
Journal of the American Chemical Society 2000 122(24): 5883-5884

(19) “Resonance assignments, secondary structure and 15N relaxation data of the human transcriptional coactivator hMBF1 (57-148).”
Masaki Mishima, Jun Ozaki, Takahisa Ikegami, Yasuaki Kabe, Masahide Goto, Hitoshi Ueda, Susumu Hirose, Hiroshi Handa and Masahiro Shirakawa
Journal of Biomolecular NMR 1999 14 (4):373-376

(20) “Identification of the core domain and the secondary structure of the transcriptional coactivator MBF1.”
Jun Ozaki, Ken-ichi Takemaru, Takahisa Ikegami, Masaki Mishima, Hitoshi Ueda, Susumu Hirose, Yasuaki Kabe, Hiroshi Handa and Masahiro Shirakawa
Genes to Cells 4(7):415-424 (1999)

(21) “新規カルシウム結合蛋白質によるNa+/H+交換輸送体の機能制御機構” (総説)
蛋白質核酸酵素 2006年 4月号 Vol.51 No.4
清水敏之・三島正規

(22) “Studies of DNA recognition mechanism of transcription factor IRF-4 .”
Kyouko Fruita, Itsuko Ishizaki, Harumi Fukada, Makoto Nomura, Kazuo Yamamoto, Toshifumi Matsuyama, Masaki Mishima and Chojiro Kojima
Nucleic Acids Symposium Series 2006 50:259-260

(23) “Solution structure of a small-molecular ligand complexed with CAG trinucleotide repeat DNA.”
Kazuhiko Nakatani, Shinya Hagihara, Yuki Goto, Akio Kobori, Masaki Hagihara, Gosuke Hayashi, Motoki Kyo, Makoto Nomura, Masaki Mishima, and Chojiro Kojima
Nucleic Acids Symposium Series 2005 48:49-50

(24) “Solution NMR study of DNA recognition mechanism of IRF4 protein.”
Itsuko Ishizaki, Makoto Nomura, Kazuo Yamamoto, Toshifumi Matsuyama, Masaki Mishima and Chojiro Kojima
Nucleic Acids Symposium Series 2004 48:105-106

(25) “多次元NMRによる水素結合の直接測定” (総説)
生物工学会誌 2003 81:142-145 .
三島正規
受 賞第44回NMR討論会若手ポスター賞(2005年11月横浜)
主な学会活動(1)日本核磁気共鳴学会
(2)日本分子生物学会
(3)日本生物物理学会
(4)日本生化学学会
(5)日本化学会
社会等との関わり第1回若手NMR研究会 主催(2000年6月京都)
第5回若手NMR研究会 講師(2004年6月箱根)
第45回NMR討論会 チュートリアルコース講師(2005年11月京都)
など
個人のURL
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  • 化学セミナー
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  • 理科教育法B
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  • 化学特別セミナーII
  • 化学特別セミナーIII
  • 化学特別セミナーIV
  • 化学特別セミナーII
  • 化学特別セミナーI
  • 化学特別セミナーIV
  • 化学特別セミナーIII
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