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阿部 拓也

氏 名阿部 拓也アベ タクヤあべ たくや
職 位助教
所 属首都大学東京都市教養学部 理工学系 化学コース
理工学研究科 分子物質化学専攻
 
専門・研究分野生物化学
最終学歴・学位東北大学大学院薬学研究科生命薬学専攻・博士
研究テーマ姉妹染色分体間接着の制御機構の解明
研究キーワードコヒーシン DNA複製 DNA修復 DT40 
研究業績・著書・
論文、その他
それに準じる業績
1, WRN counteracts the NHEJ pathway upon camptothecin exposure.
Otsuki M, Seki M, Kawabe Y, Inoue E, Dong YP, Abe T, Kato G, Yoshimura A, Tada S, Enomoto T.
Biochemical and Biophysical Researgh Communications 2007

2, Analyses of functional interaction between RECQL1, RECQL5, and BLM which physically interact with DNA topoisomerase IIIalpha.
Otsuki M, Seki M, Inoue E, Abe T, Narita Y, Yoshimura A, Tada S, Ishii Y, Enomoto T.
Biochimica et Biophysica Acta 2008

3, KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation.
Abe T, Ishiai M, Hosono Y, Yoshimura A, Tada S, Adachi N, Koyama H, Takata M, Takeda S, Enomoto T, Seki M.
Cellular Signalling 2008

4, Generation and characterization of cells that can be conditionally depleted of mitochondrial SOD2.
Takada S, Inoue E, Tano K, Yoshii H, Abe T, Yoshimura A, Akita M, Tada S, Watanabe M, Seki M, Enomoto T.
Biochemical and Biophysical Researgh Communications 2009

5, A novel role for Rad17 in homologous recombination.
Nishino K, Inoue E, Takada S, Abe T, Akita M, Yoshimura A, Tada S, Kobayashi M, Yamamoto K, Seki M, Enomoto T.
Genes & Genetic Systems 2008

6, The N-terminal region of RECQL4 lacking the helicase domain is both essential and sufficient for the viability of vertebrate cells. Role of the N-terminal region of RECQL4 in cells.
Abe T, Yoshimura A, Hosono Y, Tada S, Seki M, Enomoto T.
Biochimica et Biophysica Acta 2011

7, The role of SNM1 family nucleases in etoposide-induced apoptosis.
Hosono Y, Abe T, Ishiai M, Takata M, Enomoto T, Seki M.
Biochemical and Biophysical Researgh Communications 2011
※Co-first author

8, The histone chaperone facilitates chromatin transcription (FACT) protein maintains normal replication fork rates.
Abe T, Sugimura K, Hosono Y, Takami Y, Akita M, Yoshimura A, Tada S, Nakayama T, Murofushi H, Okumura K, Takeda S, Horikoshi M, Seki M, Enomoto T.
The Journal of Biological Chemistry 2011

9, Functional relationship between Claspin and Rad17.
Yoshimura A, Akita M, Hosono Y, Abe T, Kobayashi M, Yamamoto K, Tada S, Seki M, Enomoto T.
Biochemical and Biophysical Researgh Communications 2011

10, The SUMO protease SENP1 is required for cohesion maintenance and mitotic arrest following spindle poison treatment.
Era S, Abe T, Arakawa H, Kobayashi S, Szakal B, Yoshikawa Y, Motegi A, Takeda S, Branzei D. 
Biochemical and Biophysical Researgh Communications 2012

11, Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents.
Hosono Y, Abe T, Ishiai M, Islam MN, Arakawa H, Wang W, Takeda S, Ishii Y, Takata M, Seki M, Enomoto T.
Biochim Biophys Acta. 2014

12, Tipin functions in the protection against topoisomerase I inhibitor.
Hosono Y, Abe T, Higuchi M, Kajii K, Sakuraba S, Tada S, Enomoto T, Seki M.
J Biol Chem. 2014
※Co-first author

13, High levels of BRC4 induced by a Tet-On 3G system suppress DNA repair and impair cell proliferation in vertebrate cells.
Abe T, and Branzei D.
DNA Repair (Amst). 2014
※Corresponding author
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